In a recent study, researchers discovered that more than half of the nutritional supplements tested did not disintegrate properly. Included in the test were 39 tablets and 10 capsules containing minerals and vitamins commercially available on the Canadian market. USANA's Multimineral was included in the test. The first disintegration stage was performed using Simulated Intestinal Fluid (SIF) pH 6.8 for 20 minutes. Products which did not disintegrate were further analyzed using USP disintegration conditions for dietary supplements. Of the 39 tablets tested, only 18 products (which included Usana's Multimineral) disintegrated fully at the first stage. The 21 tablets that did not pass the first stage were then tested for disintegration using USP conditions. Nine tablets still failed to disintegrate, including all three timed-release products tested. Forty-percent of the capsules also failed the first stage, although all ten eventually passed when subjected to USP testing conditions.
This study illustrates that disintegration, one basic indicator of product quality, is still a concern for dietary supplements.
J Pharm Pharmaceut Sci (www.cspsCanada.org) 9(1):40-49, 2006
It's important to do your research before beginning any dietary or nutritional supplement regime. The editors at TCGWN recommend products manufactured by Usana Health Sciences as they are certified by NSF for quality and rated #1 in independent nutritional rankings.